Drug delivery
As an expert in oral solid dosage form development and based on its PDG Technology™, Atacama Labs offers you
The PDG granules are both flowable and compactable and can be further processed with other "add-on" technologies (i.e. retard, spray coating, etc).
Our capabilities include:
Tablets with high drug-loading can be compressed from an API granulated via PDG Technology™ with its platform excipients. The tablets have a number of excellent properties compared to existing products:
Using the PDG Technology™, one can control the particle size distribution of the granules (mean size of the granules ranging from 100 to 1100 µm).
- Tablets with controlled disintegration profiles - from oral disintegrating (ODT, FDDT) to slow release
- Fixed-dose combinations
- Capsules and capsule fillings
The PDG granules are both flowable and compactable and can be further processed with other "add-on" technologies (i.e. retard, spray coating, etc).
Our capabilities include:
- Scientific, regulatory, and product development expertise
- Proprietary technologies to enhance product performance and extend the product life-cycle
- Critical mass of facilities and personnel to conduct your project according to your requirements
- State-of-the-art facilities and equipment
- Personalized project management
Unique tablets with high drugload and fast release
PDG Technology™ opens up new opportunities in drug delivery. The technology enables development of tablets that can have- High drug-load (70-95%) and
- Disintegration time of less than 30 seconds (ODT) or
- Disintegration time up to several hours (retard)
Tablets with high drug-loading can be compressed from an API granulated via PDG Technology™ with its platform excipients. The tablets have a number of excellent properties compared to existing products:
- Convenient tablet size for patients
- Fast disintegration
- Optimal dissolution
- Good content uniformity
- Satisfying tensile strength
- Low friability
- Excellent stability
Granules for capsule filling
Formulations, that have been granulated using PDG Technology™ can be readily used for encapsulation. The dry granulated mass can contain up to 100% of the API depending on the product specifications. The granules are ready to be filled into capsules.Using the PDG Technology™, one can control the particle size distribution of the granules (mean size of the granules ranging from 100 to 1100 µm).
